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Sovereign AI for
Healthcare
Health systems do not buy AI, they buy back the hours clinicians and staff lose to coding, prior auth, and documents no one has time to read. Predictive, generative, and agentic AI that runs inside your walls, cited and explainable, with PHI that never leaves your control.





- H2O AI is the trusted Sovereign AI Platform for providers, payers, and life sciences: PHI stays inside your own walls, on your infrastructure, air-gapped where required.
- H2O AI runs Document AI over clinical documentation and payer correspondence, citing every finding to the rule that governs payment, on top of Epic and your billing system.
- The H2O AI Super Agent answers questions from your own policies, protocols, and contracts with the clause cited, so clinicians and staff stop being a search engine.
- Predictive AI keeps clinical and operational risk models, from sepsis to readmission, scoring on current patient data, explainable and auditable.
H2O AI delivers business value fast
- 01Get paid for the care you deliveredScore coding and risk adjustment against the rules that govern payment, cutting denials and recovering earned revenue.
- 02Give clinicians back their hoursAnswer the repetitive questions from your own policies and protocols, so nurses and staff stop being a search engine.
- 03Catch clinical risk earlierPredict sepsis, readmission, and length of stay with explainable models that keep scoring against current patient data.
- 04PHI never leaves your wallsRun air-gapped and sovereign on top of Epic and your existing systems, with an audit trail your compliance team accepts.
“When we started this journey, we were hopeful that information extraction from semi-structured documents was possible, but we weren't sure. Now that the UCSF-H2O.ai collaboration team has delivered, it opens up many possibilities.”Bob Rogers, PhDExpert in Residence for AI, UCSF
Key problems we solve for healthcare
Fraud prevention
Care gets delivered, then the money fights to catch up: coding that misses the rule, prior auths that stall, and denials climbing faster than the team can appeal. Read the chart against the rules that govern payment, and get paid correctly for the care you already gave.
Use the H2O AI platform to run Document AI over the clinical documentation and payer correspondence, with every finding cited to the rule that governs it. It sits on top of Epic and the billing system, never replacing them, and keeps PHI inside your own walls.

Patient and care team
The same questions come back every week, from nurses, from staff, and now from patients, while the answer already sits in a contract, a policy, or a protocol nobody has time to search. Answer it out of your own documents, with the clause cited every time.
Use the H2O AI Super Agent over your own contracts, policies, and protocols to return cited answers with the clause and the source, running air-gapped where required, with role-based access that honors existing permissions. The experts stop being a search engine, and no record leaves the organization.
Agentic automation
Invoices pile up against purchase orders no one can match, while the risk models that flag sepsis or a readmission drift out of date the moment someone stops rebuilding them. Turn the documents into something a system can act on, and keep the models scoring on current data.
Use the H2O AI platform to run Document AI for extraction and reconciliation, and Predictive AI for clinical and operational risk models that keep scoring on current data. It sits on top of your ERP, inventory, and Epic, never replacing them, and every model decision stays explainable and auditable.
Use cases by department
Each part of the business has its own problems, data, and rules. Start with your department.
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Frequently asked questions
H2O AI is a Sovereign AI Platform, so it deploys on-premises, in your private cloud, or fully air-gapped, on top of Epic and your existing systems. Your PHI never leaves your control, and every model decision stays explainable with an audit trail your compliance team accepts.